Quick Reference

HIV PrEP Fundamentals Overview

Target Audience

In this 6-hour module, novice-to-expert health care professionals can develop proficiency in the fundamental skills needed to assess, initiate, and monitor HIV PrEP. Learners who complete all 5 lessons in this module may take the optional knowledge assessment test and earn an HIV PrEP Training Certificate.

Editor

David H. Spach, MD

David H. Spach, MD
Editor-in-Chief
Professor of Medicine
Division of Allergy & Infectious Diseases
University of Washington

Disclosures: None

1Lesson 1 Basic Principles and Rationale for HIV PrEP

Learning Objectives
- Define HIV PrEP and describe the potential role of HIV PrEP in reducing new HIV infections
- State the HIV PrEP goal as described in the Ending the HIV Epidemic (EHE) initiative in the United States
- Discuss the major studies demonstrating HIV PrEP efficacy and safety
- Examine the barriers that impact HIV PrEP uptake
- Summarize strategies to reduce barriers related to HIV PrEP access and usage
Quick ReferenceBasic Principles and Rationale for HIV PrEP Core Concepts

2Lesson 2 Identifying Candidates for HIV PrEP

Learning Objectives
- Discuss HIV PrEP with all sexually active adolescents and adults and persons who inject drugs
- Summarize key epidemiology features of persons newly diagnosed with HIV in the United States
- State the Ending HIV Epidemic initiative goals for reducing HIV infections in the United States by 2025 and 2030
- Identify factors associated with sexual activity that may increase the risk of HIV acquisition
- Summarize the CDC guideline recommendations for assessing HIV PrEP eligibility and initiation
Quick ReferenceIdentifying Candidates for HIV PrEP Core Concepts

3Lesson 3 HIV PrEP Medications and Dosing Options

Learning Objectives
- List the four medications approved by the U.S. Food and Drug Administration (FDA) for HIV PrEP
- Explain the indications, dosing, and formulations, for FDA-approved HIV PrEP medications
- Discuss the issues and recommendations for HIV PrEP usage in persons with renal impairment
- Describe on-demand (2-1-1) HIV PrEP
- Summarize the multiple factors to consider when choosing HIV PrEP medications for selected patients
Quick ReferenceHIV PrEP Medications and Dosing Options Core Concepts
Activity 3B.Mechanism of Action of HIV PrEP Medications

4Lesson 4 Baseline Evaluation and Starting HIV PrEP

Learning Objectives
- Provide a rationale for obtaining baseline laboratory studies prior to starting HIV PrEP
- List the 2021 and 2025 CDC recommendations for baseline laboratory tests prior to initiating specific HIV PrEP regimens
- Summarize CDC recommendations for prescribing oral and injectable HIV PrEP, follow-up monitoring, and strategies for providing adherence support
- Define and describe same-day HIV PrEP, including protocols and exclusions for initiating same-day HIV PrEP
- Explore the concept of "time to protection" for oral and injectable HIV PrEP
Quick ReferenceBaseline Evaluation and Starting HIV PrEP Core Concepts
Activity 4B.Baseline Lab when Starting Tenofovir-DF-Emtricitabine (TDF-FTC)

5Lesson 5 Follow-Up Care and Monitoring on HIV PrEP

Learning Objectives
- Explain possible models of care for follow-up of persons receiving HIV PrEP
- List recommended laboratory monitoring tests for persons receiving HIV PrEP
- Summarize challenges in HIV diagnosis in persons receiving HIV PrEP
- Describe the potential for HIV drug resistance in persons who are diagnosed with HIV after receiving HIV PrEP
- Discuss appropriate management of persons who are newly diagnosed with HIV while taking HIV PrEP
Quick ReferenceFollow-Up Care and Monitoring on HIV PrEP Core Concepts
Activity 5B.Timing of Potential HIV Acquisition in People Prescribed HIV PrEP

The Check-on-Learning Questions are short and topic related. They are meant to help you stay on track throughout each lesson and check your understanding of key concepts.

HIV PrEP Training Certificate

NASTAD

NCCC

Prime Health

Federal Resources

HIV PrEP Fundamentals Overview

Target Audience

Editor

1Lesson 1 Basic Principles and Rationale for HIV PrEP

2Lesson 2 Identifying Candidates for HIV PrEP

3Lesson 3 HIV PrEP Medications and Dosing Options

4Lesson 4 Baseline Evaluation and Starting HIV PrEP

5Lesson 5 Follow-Up Care and Monitoring on HIV PrEP

You must be signed in to customize your interaction with these questions.

HIV PrEP Training Certificate

NASTAD

NCCC

Prime Health

Federal Resources

HIV PrEP Fundamentals Overview

Target Audience

Editor

1Lesson 1 Basic Principles and Rationale for HIV PrEP

2Lesson 2 Identifying Candidates for HIV PrEP

3Lesson 3 HIV PrEP Medications and Dosing Options

4Lesson 4 Baseline Evaluation and Starting HIV PrEP

5Lesson 5 Follow-Up Care and Monitoring on HIV PrEP

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