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- Module 1 Overview
HIV PrEP Fundamentals - 0%Lesson 1
Basic Principles and Rationale for HIV PrEPActivities- 0%Lesson 2
Identifying Candidates for HIV PrEPActivities- 2A.Core Concepts
- 2B.Using HIV PrEP Screening Tool
- 2C.The 6 Ps: A New Approach to Sexual History Taking
- 0%Lesson 3
HIV PrEP Medications and Dosing OptionsQuick ReferenceHIV PrEP Fundamentals Overview
Module Core Competency
Target Audience
In this 6-hour module, novice-to-expert health care professionals can develop proficiency in the fundamental skills needed to assess, initiate, and monitor HIV PrEP. Learners who complete all 5 lessons in this module may take the optional knowledge assessment test and earn an HIV PrEP Training Certificate.Editor
David H. Spach, MDDavid H. Spach, MD
Editor-in-Chief
Professor of Medicine
Division of Allergy & Infectious Diseases
University of WashingtonDisclosures: None1Lesson 1 Basic Principles and Rationale for HIV PrEP
- Learning Objectives
- Define HIV PrEP and describe the potential role of HIV PrEP in reducing new HIV infections
- State the HIV PrEP goal as described in the Ending the HIV Epidemic (EHE) initiative in the United States
- Discuss the major studies demonstrating HIV PrEP efficacy and safety
- Examine the barriers and disparities that impact HIV PrEP uptake
- Summarize strategies to reduce stigma and barriers related to HIV PrEP access and usage
- Quick ReferenceBasic Principles and Rationale for HIV PrEP Core Concepts
- Activity 1B.Status Neutral Approach Concept
2Lesson 2 Identifying Candidates for HIV PrEP
- Learning Objectives
- Discuss HIV PrEP with all sexually active adolescents and adults and persons who inject drugs
- Summarize key epidemiology features of persons newly diagnosed with HIV in the United States
- State the Ending HIV Epidemic initiative goals for reducing HIV infections in the United States by 2025 and 2030
- Identify factors associated with sexual activity that may increase the risk of HIV acquisition
- Summarize the CDC guideline recommendations for assessing HIV PrEP eligibility and initiation
- Quick ReferenceIdentifying Candidates for HIV PrEP Core Concepts
- Activity 2B.Using HIV PrEP Screening Tool
- Activity 2C.The 6 Ps: A New Approach to Sexual History Taking
3Lesson 3 HIV PrEP Medications and Dosing Options
- Learning Objectives
- List the three medications approved by the U.S. Food and Drug Administration (FDA) for HIV PrEP
- Explain the indications, dosing, and formulations, for FDA-approved HIV PrEP medications
- Discuss the issues and recommendations for HIV PrEP usage in persons with renal impairment
- Describe on-demand (2-1-1) HIV PrEP
- Summarize the multiple factors to consider when choosing HIV PrEP medications for selected patients
- Quick ReferenceHIV PrEP Medications and Dosing Options Core Concepts
- Activity 3B.Medications: Mechanism of Action
4Lesson 4 Baseline Evaluation and Starting HIV PrEP
- Learning Objectives
- Provide a rationale for obtaining baseline laboratory studies prior to starting HIV PrEP
- List the 2021 CDC recommendations for baseline laboratory tests prior to initiating HIV PrEP based on the specific HIV PrEP regimen to be prescribed
- Summarize CDC recommendations for prescribing oral and injectable HIV PrEP, follow-up monitoring, and strategies for providing adherence support
- Define and describe same-day HIV PrEP, including protocols and exclusions for initiating same-day HIV PrEP
- Explore the concept of "time to protection" for oral and injectable HIV PrEP
- Quick ReferenceBaseline Evaluation and Starting HIV PrEP Core Concepts
- Activity 4B.Baseline Lab when Starting Tenofovir-DF-Emtricitabine (TDF-FTC)
5Lesson 5 Follow-Up Care and Monitoring on HIV PrEP
- Learning Objectives
- Explain possible models of care for follow-up of persons receiving HIV PrEP
- List recommended laboratory monitoring tests for persons receiving HIV PrEP
- Summarize challenges in HIV diagnosis in persons receiving HIV PrEP
- Describe the potential for HIV drug resistance in persons who are diagnosed with HIV after receiving HIV PrEP
- Discuss appropriate management of persons who are newly diagnosed with HIV while taking HIV PrEP
- Quick ReferenceFollow-Up Care and Monitoring on HIV PrEP Core Concepts
- Models for Follow-Up Care in Persons Receiving HIV PrEP
- Follow-Up and Monitoring of Persons Receiving HIV PrEP
- Discontinuing HIV PrEP
- Acquisition of HIV in Persons Prescribed HIV PrEP
- Diagnosing HIV in Persons Prescribed HIV PrEP
- HIV Drug Resistance in Persons Prescribed HIV PrEP
- Management of Persons on HIV PrEP Newly Diagnosed with HIV
- HIV PrEP Tools for Clinicians: Laboratory Monitoring
- Summary Points
- Activity 5B.Timing of Potential HIV Acquisition in People Prescribed HIV PrEP
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- 0%Lesson 2
The National HIV PrEP Curriculum is supported by the Centers for Disease Control and Prevention (CDC) and the Health Resources and Services Administration (HRSA) of the U.S. Department of Health and Human Services (HHS) as part of a financial assistance award totaling $625,000 from CDC and $300,005 from HRSA with 0% financed with non-governmental sources. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement, by CDC, HRSA, HHS, or the U.S. Government. This project is led by the University of Washington Infectious Diseases Education & Assessment (IDEA) Program.
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